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Modelling non-linear exposure-disease relationships in a large individual participant meta-analysis allowing for the effects of exposure measurement error
(University of CambridgeDepartment of Pure Mathematics and Mathematical StatisticsMRC Biostatistics Unit, 2012-10-09)
This thesis was motivated by data from the Emerging Risk Factors Collaboration (ERFC), a
large individual participant data (IPD) meta-analysis of risk factors for coronary heart disease(CHD). Cardiovascular disease is the ...
Brownian motion and multidimensional decision making
(University of CambridgeJudge Business SchoolKing's CollegeElectricity Policy Research Group (EPRG), 2012-05-08)
This thesis consists of three self-contained parts, each with its own abstract, body, references and page numbering. Part I, "Potential theory, path integrals and the Laplacian of the indicator", ...
Slum upgrading in India and Kenya: investigating the sustainability
(University of CambridgeDepartment of EngineeringCentre for Sustainable DevelopmentSt Edmund's College, 2012-04-10)
Slums are informal housing settlements commonly found in urban areas of developing countries which are characterised by poor shelter, low service provision and lacking in security of tenure. Slums are growing and new slums ...
Forcing of globally unstable jets and flames
(University of CambridgeDepartment of EngineeringEmmanuel CollegeGates Scholar, 2012-04-10)
In the analysis of thermoacoustic systems, a flame is usually characterised
by the way its heat release responds to acoustic forcing. This
response depends on the hydrodynamic stability of the flame. Some
flames, such ...
A biosynthetic approach to the discovery of novel bioactive peptides
(University of CambridgeDepartment of Chemical Engineering and Biotechnology, 2012-05-08)
Peptides represent a source of novel therapeutics for recalcitrant human diseases, but screening for bioactivity from natural or synthetic sources can be uneconomic. In contrast, in vivo expression of peptides from DNA ...
The application of selective reaction monitoring shows dysregulation of glycolysis in a preclinical model of schizophrenia
(2012-03-15)
Abstract Background Establishing preclinical models is essential for novel drug discovery in schizophrenia. Most existing models are characterized by abnormalities in behavioral readouts, which are informative, but do not ...
Guessing human-chosen secrets
(University of CambridgeFaculty of Computer Science and TechnologyComputer Laboratory, 2012-06-12)
Authenticating humans to computers remains a notable weak point in computer security despite decades of effort. Although the security research community has explored dozens of proposals for replacing or strengthening ...
A cybernetic perspective on methods and process models in collaborative designing
(2012-05)
Cybernetic thinking provides a framework to understand the issues in creating and using methods and process models during collaborative designing. It can help understand what takes place while the creation and use is ...
Submarine landslide flows simulation through centrifuge modelling
(University of CambridgeDepartment of Engineering, 2012-05-08)
Landslides occur both onshore and offshore. However, little attention has been given
to offshore landslides (submarine landslides). Submarine landslides have significant
impacts and consequences on offshore and coastal ...
Design of robust service operations using cybernetic principles and simulation
(2012-05)
Information flows in a service organisation allow business units to co-ordinate their response to changes in the operating environment. Processes and interactions can be designed so that the right information flows to the ...