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Classical and thermodynamic stability of black holes
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsHughes Hall, 2010-07-06)
We consider the stability of black holes within both classical general relativity and the semiclassical thermodynamic description. In particular, we study linearised perturbations and their contribution to the gravitational ...
Scattering of internal gravity waves
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsSelwyn College, 2011-04-19)
Internal gravity waves play a fundamental role in the dynamics of stably stratified regions
of the atmosphere and ocean. In addition to the radiation of momentum and energy remote from
generation sites, internal waves ...
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta
(2010-04-19)
Abstract Background Imprinted genes show expression from one parental allele only and are important for development and behaviour. This extreme mode of allelic imbalance has been described for approximately 56 human genes. ...
Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer
(2011-02-14)
Abstract Background Inhibitors of the kinase mTOR, such as rapamycin and everolimus, have been used as cancer therapeutics with limited success since some tumours are resistant. Efforts to establish predictive markers to ...
New approaches to higher-dimensional general relativity
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2011-06-07)
This thesis considers various aspects of general relativity in more than four spacetime dimensions.
Firstly, I review the generalization to higher dimensions of the algebraic classification of the Weyl tensor and the ...
Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
(2010-05-26)
Abstract Background High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explore several data sets which make use ...
Geometric aspects of gauge and spacetime symmetries
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsTrinity College, 2011-06-07)
We investigate several problems in relativity and particle physics where symmetries play a central role; in all cases geometric properties of Lie groups and their quotients are related to physical effects. The first part ...
Thermodynamic and hydrodynamic behaviour of interacting Fermi gases
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2012-01-10)
Fermionic matter is ubiquitous in nature, from the electrons in metals and semiconductors or the neutrons in the inner crust of neutron stars, to gases of fermionic atoms, like 40K or 6Li that can be created and studied ...
Exploring nonlinear regression methods, with application to association studies
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsSt. Catharine's College, 2011-07-12)
The field of nonlinear regression is a long way from reaching a consensus. Once a method decides to explore nonlinear combinations of predictors, a number of questions are raised, such as what nonlinear combinations to ...