Browsing Department of Materials Science and Metallurgy by Author "Pacini, Clare"
Now showing items 1-2 of 2
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Empirical Bayes method for reducing false discovery rates of correlation matrices with block diagonal structure
(BioMed CentralBMC Bioinformatics, 2017-04-12)$\textbf{Background:}$ Correlation matrices are important in inferring relationships and networks between regulatory or signalling elements in biological systems. With currently available technology sample sizes for ...
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Inferring condition specific regulatory networks with small sample sizes: a case study in bacillus subtilis and infection of mus musculus by the parasite Toxoplasma gondii
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsDowning College, 2017-10-23)Modelling interactions between genes and their regulators is fundamental to understanding how, for example a disease progresses, or the impact of inserting a synthetic circuit into a cell. We use an existing method to infer ...