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Instabilities and transport in magnetized plasmas
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsDarwin College, 2011-02-08)
In a magnetized plasma, naturally occurring pressure anisotropies facilitate in- stabilities that are expected to modify the transport properties of the system. In this thesis we examine two such instabilities and, where ...
Spreading of viscous fluids and granular materials on slopes
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2010-11-16)
Materials can flow down a slope in a wide range of geophysical and industrial contexts, including lava flows on volcanoes and thin films on coated surfaces. The aim of my research is to provide quantitative insight into ...
The solar tachocline: a self-consistent model of magnetic confinement
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsQueens' College, 2011-01-11)
In this dissertation we consider the dynamics of the solar interior, with particular focus on angular momentum balance and magnetic field confinement within the tachocline.
In Part I we review current knowledge of the ...
Modified Fourier expansions: theory, construction and applications
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2010-10-12)
Modified Fourier expansions present an alternative to more standard algorithms for the approximation of nonperiodic functions in bounded domains. This thesis addresses the theory of such expansions, their effective ...
Classical and thermodynamic stability of black holes
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsHughes Hall, 2010-07-06)
We consider the stability of black holes within both classical general relativity and the semiclassical thermodynamic description. In particular, we study linearised perturbations and their contribution to the gravitational ...
Scattering of internal gravity waves
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsSelwyn College, 2011-04-19)
Internal gravity waves play a fundamental role in the dynamics of stably stratified regions
of the atmosphere and ocean. In addition to the radiation of momentum and energy remote from
generation sites, internal waves ...
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta
(2010-04-19)
Abstract Background Imprinted genes show expression from one parental allele only and are important for development and behaviour. This extreme mode of allelic imbalance has been described for approximately 56 human genes. ...
Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer
(2011-02-14)
Abstract Background Inhibitors of the kinase mTOR, such as rapamycin and everolimus, have been used as cancer therapeutics with limited success since some tumours are resistant. Efforts to establish predictive markers to ...
New approaches to higher-dimensional general relativity
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2011-06-07)
This thesis considers various aspects of general relativity in more than four spacetime dimensions.
Firstly, I review the generalization to higher dimensions of the algebraic classification of the Weyl tensor and the ...