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Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
(2010-05-26)
Abstract Background High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explore several data sets which make use ...
Geometric aspects of gauge and spacetime symmetries
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsTrinity College, 2011-06-07)
We investigate several problems in relativity and particle physics where symmetries play a central role; in all cases geometric properties of Lie groups and their quotients are related to physical effects. The first part ...
Thermodynamic and hydrodynamic behaviour of interacting Fermi gases
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2012-01-10)
Fermionic matter is ubiquitous in nature, from the electrons in metals and semiconductors or the neutrons in the inner crust of neutron stars, to gases of fermionic atoms, like 40K or 6Li that can be created and studied ...
Exploring nonlinear regression methods, with application to association studies
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsSt. Catharine's College, 2011-07-12)
The field of nonlinear regression is a long way from reaching a consensus. Once a method decides to explore nonlinear combinations of predictors, a number of questions are raised, such as what nonlinear combinations to ...
Tidal interactions between planets and stars
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsSelwyn College, 2011-06-07)
Since the first discovery of an extrasolar planet around a solar-type star, observers
have detected over 500 planets outside the solar system. Many of these planets have
Jovian masses and orbit their host stars in orbits ...
The application of automated perturbation theory to lattice QCD
(University of CambridgeDepartment of Applied Mathematics and Theoretical PhysicsTrinity College, 2011-11-08)
Predictions of heavy quark parameters are an integral component of precision
tests of the Standard Model of particle physics. Experimental measurements
of electroweak processes involving heavy hadrons provide stringent ...
On some partial differential equation models in socio-economic contexts - analysis and numerical simulations
(University of CambridgeDepartent of Applied Mathhematics and Theoretical PhysicsTrinity College, 2012-01-10)
This thesis deals with the analysis and numerical simulation of different partial differential equation models arising in socioeconomic sciences. It is divided into two parts: The first part deals with a mean-field price ...
Spiky strings and the AdS/CFT correspondence
(University of CambridgeDepartment of Applied Mathematics and Theoretical Physics, 2011-10-11)
In this dissertation, we explore some aspects of semiclassical type IIB string
theory on AdS3 × S1 and on pure AdS3 in the limit of large angular momentum
S.
We first focus on the integrability technique known as ...
A simple Bayesian estimate of direct RNAi gene regulation events from differential gene expression profiles
(2011-05-20)
Abstract Background Microarrays are commonly used to investigate both the therapeutic potential and functional effects of RNA interfering (RNAi) oligonucleotides such as microRNA (miRNA) and small interfering RNA (siRNA). ...