Abstract Background Grouping genes into clusters on the basis of similarity between their expression profiles has been the main approach to predict functional modules, from which important inference or further investigation ...

Tissue engineering offers a paradigm shift in the treatment of back pain. Engineered intervertebral discs could replace degenerated tissue and overcome the limitations of current treatments that disrupt the biomechanics ...

Plastics play an enormous role in modern manufacturing, but the extraction and refining of raw materials, followed by the synthesis of plastics themselves, represents an enormous energy investment into a product that is ...

In a hostile environment, it is important for a transmitter to make its wireless transmission invisible to adversaries because an adversary can detect the transmitter if the received power at its antennas is strong enough. ...

The coalescence and mixing of a sessile and an impacting liquid droplet on a solid surface are studied experimentally and numerically in terms of lateral separation and droplet speed. Two droplet generators are used to ...

The performance of product development processes is important to the commercial success of new products. The improvement of these processes is thus a strategic imperative for many engineering companies — the aero-engine ...

Abstract Background During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively). The ...

In the last decade, efficient use of energy has become a topic of global significance, touching almost every area of modern life, including computing. From mobile to desktop to server, energy efficiency concerns are now ...

This paper examines design iteration and its modelling in the simulation of New Product Development (NPD) processes. A framework comprising six perspectives of iteration is proposed and it is argued that the importance of ...

A retrofitting technique has been developed that uses carbon fiber-reinforced polymer (CFRP) straps to increase the shear capacity of reinforced concrete beams. The vertical straps are not bonded to the beam but are instead ...

Friction stir spot welding (FSSW) is a solid-state welding process which is especially useful for joining precipitation-hardened aluminium alloys that undergo adverse property changes during fusion welding. It also has ...

This thesis investigates the modelling of friction stir welding (FSW). FSW is a relatively new welding process where a rotating non-consumable tool is used to join two materials through high temperature deformation. The ...

Abstract Background This work focuses on the computational modelling of osteomyelitis, a bone pathology caused by bacteria infection (mostly Staphylococcus aureus). The infection alters the RANK/RANKL/OPG signalling dynamics ...

Design work involves uncertainty that arises from, and influences, the progressive development of solutions. This paper analyses the influences of evolving uncertainty levels on the design process. We focus on uncertainties ...

Morale is a commonly used term both in business and society but the concept of morale is relatively poorly defined and understood. In a recent paper Liefooghe et al. (2004) expressed surprise that ‘…when reviewing the ...

Localisation processes, such as shear banding and necking, have been investigated following a macroscopic and a microscopic approach. Both approaches have been formulated within a finite deformation plasticity framework. ...

Multi-Scale, Sustainable Reaction Engineering - A New Departmental Initiative

AbstractBackgroundBdelloid rotifers are microscopic animals that have apparently survived without sex for millions of years and are able to survive desiccation at all life stages through a process called anhydrobiosis. ...