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The Effect Of Osteogenesis on the Mechanical Properties of a 3-D Polylactic Acid Scoffold

dc.contributor.authorOgbonnia, Chinaza Esther
dc.description2021 Materials Science and Engineering masters Thesesen_US
dc.description.abstractPoly-Lactic Acid is used widely in biomedical applications due to its good biocompatibility (i.e. biological and chemical inertness) and biodegradability. The area of tissue Engineering has been explored for the regeneration of human organs and tissues. This study explores the structure and the mechanical properties of 3D PLA scaffolds that are cultured with human osteoblasts for bone regeneration. The initial stages of cell spreading and interactions are studied along with the mechanical properties of the scaffolds before and after cell spreading and interactions. The effects of simulated body fluid are also studied to provide insights into the potential degradation that can occur during exposure to human body fluids. The implications of the work are discussed for the integration of 3D PLA scaffolds during the initial stages of bone regeneration and repair.en_US
dc.subject2020 Materials Science Masters Thesesen_US
dc.subjectOgbonnia Chinaza Estheren_US
dc.subjectPoly-Lactic Acid scaffoldsen_US
dc.subjectdegradation mechanismsen_US
dc.subjecthuman osteoblastsen_US
dc.subjectcell/surface Interactionen_US
dc.subjectbone tissue regenerationen_US
dc.subjectProf. Wole Soboyejoen_US
dc.subjectDr. Shola Odusanyaen_US
dc.titleThe Effect Of Osteogenesis on the Mechanical Properties of a 3-D Polylactic Acid Scoffolden_US

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